Semaglutide vs. Tirzepatide: All Your Questions Answered

Weight loss is one of the biggest and most common struggles Americans face. Statistics indicate that nearly half of American adults tried to lose weight within the past 12 months.

The continuous battle with extra pounds is exhausting and often disappointing.

Weight loss involves multiple variables that vary from person to person. Hormones and hunger cues affect people differently. For example, low levels of leptin, the hormone that tells the brain it’s time to stop eating, could be the culprit.

Our experts understand that weight gain is not only a matter of motivation and discipline. Many people have tried all their lives to lose weight but can’t identify the variables blocking their efforts. 

Fortunately, drugs previously used for the management of diabetes have been shown to help people struggling with excess weight as well. 

If you’re considering one of these medications, read on. Our North Tex MedCare Clinic & Urgent Care expert, Dr. Frank Lee, answers your questions about semaglutide and tirzepatide.

How do semaglutide and tirzepatide work?

Semaglutide increases insulin secretion, slows digestion, and increases satiety. Tirzepatide has the same effects but is stronger, increasing insulin secretion even further. Both are good options for blood sugar management.

How does it feel to be on semaglutide and tirzepatide?

Both drugs are appetite suppressants. They make you feel fuller for longer and reduce your food cravings.

If you have energy crashes due to poor blood sugar management, these drugs can also help you maintain steadier energy levels throughout the day.

Both drugs have similar side effects, including nausea, gastrointestinal upset, and vomiting. However, not everyone experiences these side effects, with nausea being the most common.

How are semaglutide and tirzepatide administered for weight loss?

Both are given as a subcutaneous injection once per week. Usually, you start with a smaller dose and move your way up as your body adjusts to it.

Are both medications equally effective?

Both are effective at causing weight loss, but tirzepatide is slightly more effective as it works on two receptors and stimulates insulin in larger amounts than semaglutide.

Get support on your weight loss journey

Our providers empathize with the struggles of many Americans trying to lose weight and offer several weight-loss medications, including semaglutide and tirzepatide. Based on your medical history and consultation, our providers will let you know which medication would work best for your weight loss goals.

Contact us to schedule an appointment to have a dedicated medical team on your side as you lose weight.